Mouse freezes with drive going into high pitch spin

Hello to all .
I have been experiencing a bit of a problem...  I currently own a Toshiba Satellite U205-S5034
I test a lot of software on my machine... What I am encountering is mouse freeze as i rapidly zip
through various applications with the drive going into a high pitch spin.  The only way that I rid this
problem, I have to do a force shut down. Is there a remedy for such a problem?

Thanks, I'll try that.
I want to figure out also why I'm having this problem (sounds like speaker wires have been crossed!). When I used Compressor, I selected 'DVD Fatest Encode 90 mins", which ended up giving me two audio files: an AC3 Audio file and an AIFF audio file. I've been using the AC3 audio file, (and the M2V video file) in DVD Studio to burn a disc.
I went backed and checked, it's the AC3 file that is screwed up; when I checked the AIFF file, the sound is fine (no buzzing).
I wonder if it's possible there's something wrong with Compressor's AC3 audio routine?

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