Mouse skipping- Wired and wireless, Snow Leopard and Lion

We purchased a new Mac Pro last year and from the beginning have had issues with the mouse skipping around while in use. Issue is intermittent. Exists whether using wired or wireless mouse and present in both of the two user profiles that we have set up. Initially we were running Snow Leopard, and now have upgraded to Lion - which hasn't made any difference. All updates have been installed.
I've tried resetting the SMC, PRAM and trashing preferences. Hardward test resulted with: 4VDC/1/40000003: VideoController
Could an issue with the video controller be causing this?
I've read a lot of discussions with various mouse issues that are similar - yet no clear resolutions.
HEEEEEEELLLLLLLLP!
Specs:
Mac Pro - Mid 2010
3.2 GHz Quad-Core Intel Xeon
16 GB 1066 MHz DDR3 EEC
ATI Radeon HD 5770 1024 MB
Mac OS X Lion 10.7.4 (11E53)

I plan to definitely have that checked out - but the machine is currently in high demand and if that is not related to the mouse issue, it will be tough to take it out of service at the time.
Do you have any idea if the video controller issue could cause this mouse issue?
Thanks for the comment.

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Mouse skipping- Wired and wireless, Snow Leopard and Lion

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