Moving OS hard drives between Macs of different makes/models

Is it okay to move the operating system hard drive (E.g. the Boot drive) from one mac to another? What about from one model of mac (E.g. a Mac Mini) to a different model. (Mac Pro) In the PC world, this is an absolute no no due to drivers, registry issues, and other problems. However, I've spoken to a couple of mac technicians who say it's perfectly acceptable and works "flawlessly."
The reason i'm asking is because we recently built a new boot drive for one of our Mac Pros (2010 model) using a Mac Mini (2012). The tech installed the OS and all the applications using his mac mini and then moved the hard drive to the mac pro. Now we are having a bunch of weird issues with this specific mac pro such as lock ups and other glitches. We are now wondering if perhaps the issue is related to the build process used.
Thanks for any advice you can provide.

MattRK wrote:
...However, I've spoken to a couple of mac technicians who say it's perfectly acceptable and works "flawlessly."...
I'd say only if you're really lucky, but since you're having issues, you apparently weren't.
...We are now wondering if perhaps the issue is related to the build process used...
As The hatter has said, you'd need the machine-specific installer (i.e., Mac OS 10.6.4) for a 2010 Mac Pro which wasn't what was done.
However, since it looks like you're using Lion now, if you download and install the 10.7.5 combo updater,  a good portion of the operating system will be replaced and customized for the Mac Pro. You can try that to see if the various glitches are cured. There are similar combo updaters for Snow Leopard and Mountain Lion which can accomplish pretty much the same thing.

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