MPN, block PO for a vendor and material (not MPN material)

Hello everyone,
I have a doubt regarding MPN process I created a MPN material referencing an internal material. I have a vendor and a manufacturer.
If I create a purchase order with the MPN material (in the line the internal material comes automatically) and vendor  and the manufacture is blocked by QM status (MP01). When I try to save the PO I receive a warning message and I am not able to save the PO. No Issues till now.
The thing is, if I create a PO with the internal material and the vendor I am able to save it, and the MPN material never comes up. And I want to be blocked also in this escenario.
thanks in advance
Sebas

Hi,
If you want that system should not allow user to create PO for the internal material and should only allow the MPN material then you can use Manufacturer's Part Profile in Internal material and MPN material and maintain Approved Manufacturer Part List (AMPL) in MP01.
You have to configure MPN Profile in SPRO > MM > Purchasing > Material Master > Define Manufacturer Part Profile
Here activate "MPN Mandatory" and rest all as per your requirement.

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