Much used, purchased version PS CS5 now refuses to start.

I'm getting the message"missing loc key" whenever I try to start up Photoshop CS5 extended 64bit. The 32bit works but everything is pretty slow. I've uninstalled/reinstalled 3 times, removed plugins , sacrificed a goat etc. I put it on a new, much better rig, but didn't unbox for a year, I solved the much dreaded "ATI AMD Radeon HD 5450" graphics card incompatibility BS, but somewhere along the line a now not so close friend attempted to install a bootleg of CS6 as a birthday present (any return favor notions most welcome). It never functioned as far as I could and see and I promptly uninstalled it, but since then, everything ain't right. I promise all the goat you can eat if you help me.
Hallal yeah!
Please don't hate me, I'm sort of crazy w/o my PS..
E

You don't know that the bootleg did. You could try using  Adobe to wipe out their products then re-install CS5,  If the does not  work you may need to wipe your system. Format your disk and do a factory restore.
Use the CC Cleaner Tool to solve installation problems | CC, CS3-CS6

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