Multiple Copies of iTunes.MSI file

I am in the process of cleaning up my older Sony Vaio system disk (XP Home), and noted I have multiple copies of iTunes.msi and Quick Time.msi files in a subdirectory entitled *'downloaded installations'*. Some dates go back to 2005. Is it advisable to delete older versions or are all versions/dates necessary to remain on the system? I also noted many ipod updater files from 2006. Are these necessary along with *restore.jpsw files to be kept? I'm hoping there is a concise file listing of whats really necessary to keep vs. install or update leftover files. Most of these are 35Meg+ so I have a lot of disk space being used right now for these older files.
Thanks in advance...............

I never noticed theose before! I had several. I got rid of them all after a quick google convinced me I'll never need them again.

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