My applications do not launch

I have creative cloud and have been using photoshop, in design and illustrator. Suddenly, none of them is opening. Please any ideas? Many thanks

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    From MacFixIt.com
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    1. Click on the afflicted application to select it in the Finder
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    * Open Audio MIDI Setup (/Applications/Utilities).
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    Check the following locations for any recently added files, or any files implicated in error messages generated when you attempt to launch the problematic application:
    * /Library/Internet Plug-ins
    * ~/Library/InputManagers
    Re-apply the Mac OS X combo updater Try re-applying the latest Mac OS X combo updater from Apple's software downloads page. Doing so can resolve issues with system components or delete specific files that can resolve application launching issues.
    Create a new user account Try creating a new user account, and check if the application launches under it. If so, a user-specific corruption issue is likely at play -- see the above sections regarding .plist files and caches.
    Archive and Install As a last resort, try performing an Archive and Install process, which will retain some user settings but otherwise leave you with a fresh Mac OS X installation.
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