My iMac seems to be running slower lately.  Does anyone have suggestions?  I ran EtreCheck and these are my results:

Hardware Information:
          iMac (27-inch, Mid 2010)
          iMac - model: iMac11,3
          1 2.8 GHz Intel Core i5 CPU: 4 cores
          4 GB RAM
Video Information:
          ATI Radeon HD 5750 - VRAM: 1024 MB
System Software:
          OS X 10.9.2 (13C64) - Uptime: 20 days 0:15:36
Disk Information:
          Hitachi HDS722020ALA330 disk0 : (2 TB)
                    EFI (disk0s1) <not mounted>: 209.7 MB
                    Macintosh HD (disk0s2) / [Startup]: 1.89 TB (1.42 TB free)
                    Recovery HD (disk0s3) <not mounted>: 650 MB
                    Untitled (disk0s4) /Volumes/Untitled: 107.05 GB (79.41 GB free)
          OPTIARC DVD RW AD-5680H 
USB Information:
          Apple Computer, Inc. IR Receiver
          Apple Inc. Built-in iSight
          Apple, Inc. Keyboard Hub
                    Apple, Inc Apple Keyboard
          Apple Internal Memory Card Reader
          Apple Inc. BRCM2046 Hub
                    Apple Inc. Bluetooth USB Host Controller
FireWire Information:
Thunderbolt Information:
Problem System Launch Agents:
          [System] com.paragon.NTFS.auth.plist 3rd-Party support link
Launch Daemons:
          [System] com.adobe.fpsaud.plist 3rd-Party support link
          [System] com.google.keystone.daemon.plist 3rd-Party support link
          [System] com.microsoft.office.licensing.helper.plist 3rd-Party support link
          [System] com.oracle.java.Helper-Tool.plist 3rd-Party support link
          [System] com.oracle.java.JavaUpdateHelper.plist 3rd-Party support link
Launch Agents:
          [System] com.google.keystone.agent.plist 3rd-Party support link
          [System] com.oracle.java.Java-Updater.plist 3rd-Party support link
          [System] com.seagate.SeagateStorageGauge.plist 3rd-Party support link
User Launch Agents:
          [not loaded] com.adobe.ARM.[...].plist 3rd-Party support link
          [not loaded] com.nds.pcshow.plist 3rd-Party support link
          [not loaded] com.nds.pcshow.uninstall.plist 3rd-Party support link
User Login Items:
          Microsoft Database Daemon
          Android File Transfer Agent
          Microsoft Word
          AdobeResourceSynchronizer
Internet Plug-ins:
          LogitechHarmony: Version: 1.0.0.1 3rd-Party support link
          o1dbrowserplugin: Version: 5.2.4.18058 3rd-Party support link
          Google Earth Web Plug-in: Version: 6.0 3rd-Party support link
          Default Browser: Version: 537 - SDK 10.9
          CouponPrinter-FireFox: Version: Version 1.1.5
          net.juniper.DSSafariExtensions: Version: (null) 3rd-Party support link
          Unity Web Player: Version: UnityPlayer version 4.3.5f1 - SDK 10.6 3rd-Party support link
          AdobePDFViewerNPAPI: Version: 11.0.06 - SDK 10.6 3rd-Party support link
          FlashPlayer-10.6: Version: 13.0.0.201 - SDK 10.6 3rd-Party support link
          Silverlight: Version: 5.1.10411.0 - SDK 10.6 3rd-Party support link
          Flash Player: Version: 13.0.0.201 - SDK 10.6 3rd-Party support link
          iPhotoPhotocast: Version: 7.0 - SDK 10.8
          googletalkbrowserplugin: Version: 5.2.4.18058 3rd-Party support link
          QuickTime Plugin: Version: 7.7.3
          AdobePDFViewer: Version: 11.0.06 - SDK 10.6 3rd-Party support link
          SharePointBrowserPlugin: Version: 14.3.8 - SDK 10.6 3rd-Party support link
          GarminGPSControl: Version: 3.0.1.0 Release - SDK 10.4 3rd-Party support link
          JavaAppletPlugin: Version: Java 7 Update 51 Outdated! Update
Audio Plug-ins:
          BluetoothAudioPlugIn: Version: 1.0 - SDK 10.9
          AirPlay: Version: 2.0 - SDK 10.9
          AppleAVBAudio: Version: 203.2 - SDK 10.9
          iSightAudio: Version: 7.7.3 - SDK 10.9
iTunes Plug-ins:
          Quartz Composer Visualizer: Version: 1.4 - SDK 10.9
3rd Party Preference Panes:
          Flash Player  3rd-Party support link
          Java  3rd-Party support link
          Paragon NTFS for Mac ® OS X  3rd-Party support link
Old Applications:
          Garmin Map Update:          Version: 4.2.0 - SDK 10.4 3rd-Party support link
                    /Users/[redacted]/Library/Application Support/Garmin/Garmin Map Update/tmp/Garmin Map Update.app
          Solver:          Version: 1.0 - SDK 10.5 3rd-Party support link
                    /Applications/Microsoft Office 2011/Office/Add-Ins/Solver.app
          SLLauncher:          Version: 1.0 - SDK 10.5 3rd-Party support link
                    /Library/Application Support/Microsoft/Silverlight/OutOfBrowser/SLLauncher.app
          /Applications/Microsoft Office 2011/Office
                    Microsoft Graph:          Version: 14.3.8 - SDK 10.5 3rd-Party support link
                    Microsoft Database Utility:          Version: 14.3.8 - SDK 10.5 3rd-Party support link
                    Microsoft Office Reminders:          Version: 14.3.8 - SDK 10.5 3rd-Party support link
                    Microsoft Upload Center:          Version: 14.3.8 - SDK 10.5 3rd-Party support link
                    My Day:          Version: 14.3.8 - SDK 10.5 3rd-Party support link
                    SyncServicesAgent:          Version: 14.3.8 - SDK 10.5 3rd-Party support link
                    Open XML for Excel:          Version: 14.3.8 - SDK 10.5 3rd-Party support link
                    Microsoft Alerts Daemon:          Version: 14.3.8 - SDK 10.5 3rd-Party support link
                    Microsoft Database Daemon:          Version: 14.3.8 - SDK 10.5 3rd-Party support link
                    Microsoft Chart Converter:          Version: 14.3.8 - SDK 10.5 3rd-Party support link
                    Microsoft Clip Gallery:          Version: 14.3.8 - SDK 10.5 3rd-Party support link
          /Applications/Microsoft Office 2011
                    Microsoft PowerPoint:          Version: 14.3.8 - SDK 10.5 3rd-Party support link
                    Microsoft Excel:          Version: 14.3.8 - SDK 10.5 3rd-Party support link
                    Microsoft Outlook:          Version: 14.3.8 - SDK 10.5 3rd-Party support link
                    Microsoft Word:          Version: 14.3.8 - SDK 10.5 3rd-Party support link
                    Microsoft Document Connection:          Version: 14.3.8 - SDK 10.5 3rd-Party support link
          Microsoft Language Register:          Version: 14.3.8 - SDK 10.5 3rd-Party support link
                    /Applications/Microsoft Office 2011/Additional Tools/Microsoft Language Register/Microsoft Language Register.app
          WFTPairing:          Version:  - SDK 10.4 3rd-Party support link
                    /Applications/Canon Utilities/EOS Utility/WFTPairing.app
          TurboTax Deluxe 2011:          Version: 2011.r15.011 - SDK 10.4 3rd-Party support link
Time Machine:
          Skip System Files: NO
          Mobile backups: OFF
          Auto backup: NO - Auto backup turned off
          Volumes being backed up:
                    Macintosh HD: Disk size: 2  Disk used: 442.83 GB
          Destinations:
                    FreeAgent GoFlex Drive [Local] (Last used)
                    Total size: 2 
                    Total number of backups: 3
                    Oldest backup: 2011-08-20 01:52:24 +0000
                    Last backup: 2013-06-08 06:03:59 +0000
                    Size of backup disk: Adequate
                              Backup size 2  > (Disk used 442.83 GB X 3)
          Time Machine details may not be accurate.
          All volumes being backed up may not be listed.
Top Processes by CPU:
               1%          WindowServer
               1%          EtreCheck
               0%          coreservicesd
               0%          dpd
Top Processes by Memory:
          209 MB          Safari
          119 MB          Finder
          106 MB          com.apple.IconServicesAgent
          74 MB          com.apple.WebKit.Networking
          61 MB          iTunes
Virtual Memory Information:
          76 MB          Free RAM
          907 MB          Active RAM
          842 MB          Inactive RAM
          571 MB          Wired RAM
          9.35 GB          Page-ins
          593 MB          Page-outs

Hi ..
User Login Items:
          Microsoft Database Daemon
          Android File Transfer Agent
          Microsoft Word
          AdobeResourceSynchronizer
Open System Preferences > Users & Groups > Login Items
Remove all items mentioned above then restart your Mac to test.

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