My imac will not restart after updating itunes. What do I do?

I have just updates iTunes to use my new iPod nano. The computer attempted to restart and I have been left with the grey apple start up screen. Is there anything that I can do to resolve this?

See if you can get back in with a Safe Boot. Shutdown (hold power button in until it does, if necessary), hold down Shift at the startup chime and give it much longer to boot. Might try repairing Permissions while in Safe Boot, from Disk Utility. Also Verify Disk. No need, as Safe Boot should do this.
After doing that, and if it will then boot normally, get the iTunes update from Apple Downloads and reapply it.
If it was the 11.01, get it here.
http://support.apple.com/kb/DL1614

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