My ipad has a screen up that says icloud has not been backed up and it will not let me do anything

My iPad has a screen up that says icloud has not been backed up in a while. I can not get that screen to close or turn off my iPad. What do I do?

Do you mean it says,
"This iPad has not been backed up in 2 weeks.
            Back up now?"
Did you try the home button?

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