My iPhone does not Sync or Charge when I plug it into my Mac

Until today it has been fine but when I connect my iPhone to my Mac nothing happens. No Sync, no opening of iTunes and no Charging. Has anyone had this happen to them and is there a solution.
Monty

UPDATE:
Okay, I finally got a solution that worked. I downloaded the latest version of AppleJack (http://www.macupdate.com/info.php/id/15667), a free utility that does a deep clean on your Mac, repairing preferences and the like, better than any other utility I've used.
You must use it in Single User UNIX mode, but this is no reason to fear it. Just hold down Command+S after the gong, when you reboot your computer. When you start seeing white text on a black background, you can let go. When the text stops scrolling, type this command at the prompt:
applejack auto restart
and hit the return key.
This tells AppleJack to run all it's routines automatically, and then reboot your Mac in OS X. It can take a little while to do it's repairs if you have a big drive. It took about 15 min. on my 500GB drive.
When it completed its tasks and rebooted, I plugged the iPhone into it's doc and it now works like a charm, syncing as we speak, and charging!
Message was edited by: Claidheamdanns - grammar fix

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