My system preferences is not working/ responding. Please help.

System Preferences is inactive. On the dock the Icon has a question mark on it.
I tried other solutions on  here, but nothing has work. Please help. Thank you
Mac OS X 10.6.8

I was asking if the problem could be reproduced in another account.  If not then we know it's something lock only to your account.  But if you don't want to create another account we'll try some alternate scheme...
Is System Preferences.app in your /Applications folder?  If it is double click it to see if it launches.
It is possible you deleted it or moved it.  That would explain the question mark in the dock since the dock entry doen't find the actual System Preference app in /Applications. 
If it isn't in /Applications you need to find it.  If it is deleted you need to reinstall it from somewhere (reinstall, or a backup for example).

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