Navigation Panel and content Area can not any more be displayed

Hello Gurus,
we have a very big prolem with our Portal in the Development.
A new colleague has probably changed some settings in the portal. Now by logging into the portal, i can only see the header Area (Masterhead, Tolls, Top-Level Navigation, Page title Bar). By clicking on the role like system Administrator, nothing is showing.
The Navigation Panel and the content area are gone. How can i restore them back?
Any Workaround?
Thanks in advance
Cheers

Hi Anja, Puneet,
thank you very much to have replied.
through the SAP Note and you path, i can access the portal again. I am not using the standard framework.
We have a customized Destop Page, Framework and after a check they still exist. Could you once advice where could be the error. Or where someone chnage the settings?
many thanks in advance.
Cheers

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