Need help: Mouse + OS freezes periodicaly every 2-3 seconds

Greetings,
my brand new MacPro arrived and I just finished installing After Effects and the Creative Suite on Friday. I left the Mac in the office, transferring my personal files from the old mac over the weekend.
Unfortunately I experience a problem today:
The Mouse and the hole System freezes for approx 0,25seconds every 3 seconds! Crazy: the pattern of stop and go is completely constant. It began with 0,25sec stop every 3 seconds and now changed into a second freeze just after the first stop, ... then 3 seconds everything seemed fine and so on ...
What I already did: I changed the USB Port of my Keyboard, changed the mouse AND keyboard, startet in SafeMode, checked whether TimeMachine is off. With no positive result.
Does anyone of you have an idea? I really need this new computing-power today for my current project.
Here a list of Sotware I installed: Adobe CS2, After Effects CS4, Firefox.
Thank YOU!

DNA. No two chips are 200% identical. When you say identical Mac, exact same process config and firmware?
When new machines ship, there may be new OS builds this week that wasn't there last week; or different firmware for EFI (or graphics cards), which can be assembled in different locations or parts.
The first thing I do after a freeze is zap pram/nvram; run an fsck or diskutil, or boot from another drive and repair. A system that has not crashed, frozen etc will have intact and the integrity of the file system. Which is why sometimes the first thing suggested is to boot from a fresh install or backup or another hard drive than the one you have.
Go to About This Mac... Command + click on "OS X version" and it will display "Build...." - in case they differ.
Changing hardware can trigger a rebuild of nvram which, just from swapping parts, can affect outcome (quantum effect of measuring (spin, charge or location), but the act itself changes what is observed).

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