No audio playback in several apps

I can't get audio playback in several streaming apps. So far it's RealPlayer, YouTube, and Google Video. They will play the video, but there is no audio, regardless of volume, muting, etc. I do have audio in QuickTime and stuff streaming through Flip4Mac.
I first noticed this yesterday, and it started for no apparent reason. I restarted, nothing. I tried restoring and reinstalling RealPlayer, and it didn't fix it either.
Any ideas on how to fix this?

I am having a similar problem - I get audio from iTunes, but not from QuickTime or RealPlayer? YouTube plays audio just fine.
My OS is at 10.4.8 to stay within the Pro Tools supported realm.
This is both for streaming and any local media - I've checked my sound prefs and all looks fine - output is to internal speakers or headphones (if plugged in).
What could this be?

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    EtreCheck version: 2.1.8 (121)
    Report generated April 16, 2015 at 11:20:10 PM CDT
    Download EtreCheck from http://etresoft.com/etrecheck
    Click the [Click for support] links for help with non-Apple products.
    Click the [Click for details] links for more information about that line.
    Hardware Information: ℹ️
        MacBook Pro (Retina, 13-inch, Late 2013) (Technical Specifications)
        MacBook Pro - model: MacBookPro11,1
        1 2.4 GHz Intel Core i5 CPU: 2-core
        16 GB RAM Not upgradeable
            BANK 0/DIMM0
                8 GB DDR3 1600 MHz ok
            BANK 1/DIMM0
                8 GB DDR3 1600 MHz ok
        Bluetooth: Good - Handoff/Airdrop2 supported
        Wireless:  en0: 802.11 a/b/g/n/ac
        Battery Health: Normal - Cycle count 298
    Video Information: ℹ️
        Intel Iris
            Color LCD spdisplays_2560x1600Retina
    System Software: ℹ️
        OS X 10.10.3 (14D131) - Time since boot: 1:26:40
    Disk Information: ℹ️
        APPLE SSD SD0256F disk0 : (251 GB)
            EFI (disk0s1) <not mounted> : 210 MB
            Macintosh HD (disk0s2) / : 150.14 GB (103.49 GB free)
            Recovery HD (disk0s3) <not mounted>  [Recovery]: 650 MB
            BOOTCAMP (disk0s4) /Volumes/BOOTCAMP : 100.00 GB (26.24 GB free)
    USB Information: ℹ️
        Apple Internal Memory Card Reader
        Apple Inc. Apple Internal Keyboard / Trackpad
        Apple Inc. BRCM20702 Hub
            Apple Inc. Bluetooth USB Host Controller
        Maxtor OneTouch 160.04 GB
            OneTouch4 Mini (disk1s1) /Volumes/OneTouch4 Mini : 160.04 GB (116.48 GB free)
        Seagate USB Mass Storage 100.03 GB
            Seagate 100 (disk2s1) /Volumes/Seagate 100 : 100.03 GB (91.52 GB free)
    Thunderbolt Information: ℹ️
        Apple Inc. thunderbolt_bus
    Gatekeeper: ℹ️
        Mac App Store and identified developers
    Kernel Extensions: ℹ️
            /System/Library/Extensions
        [not loaded]    com.bose.bluetooth (1.0.0) [Click for support]
        [not loaded]    com.marvell.kext.USBGenericPrinterClass (1.0.0) [Click for support]
    Launch Agents: ℹ️
        [loaded]    com.oracle.java.Java-Updater.plist [Click for support]
        [loaded]    org.gpgtools.gpgmail.enable-bundles.plist [Click for support]
        [loaded]    org.gpgtools.gpgmail.patch-uuid-user.plist [Click for support]
        [loaded]    org.gpgtools.Libmacgpg.xpc.plist [Click for support]
        [loaded]    org.gpgtools.macgpg2.fix.plist [Click for support]
        [running]    org.gpgtools.macgpg2.shutdown-gpg-agent.plist [Click for support]
        [loaded]    org.gpgtools.macgpg2.updater.plist [Click for support]
    Launch Daemons: ℹ️
        [loaded]    com.adobe.fpsaud.plist [Click for support]
        [running]    com.fitbit.galileod.plist [Click for support]
        [loaded]    com.oracle.java.Helper-Tool.plist [Click for support]
        [loaded]    com.oracle.java.JavaUpdateHelper.plist [Click for support]
        [loaded]    com.rogueamoeba.instanton-agent.plist [Click for support]
        [loaded]    com.sonos.smbbump.plist [Click for support]
        [loaded]    org.gpgtools.gpgmail.patch-uuid.plist [Click for support]
    User Launch Agents: ℹ️
        [loaded]    com.adobe.ARM.[...].plist [Click for support]
        [running]    com.hp.printerAgent.plist [Click for support]
    User Login Items: ℹ️
        iTunesHelper    Application  (/Applications/iTunes.app/Contents/MacOS/iTunesHelper.app)
        Dropbox    Application  (/Applications/Dropbox.app)
        Safari    Application  (/Applications/Safari.app)
        Mail    Application  (/Applications/Mail.app)
        AdobeResourceSynchronizer    Application Hidden (/Applications/Adobe Reader.app/Contents/Support/AdobeResourceSynchronizer.app)
        Fitbit Connect Menubar Helper    Application  (/Applications/Fitbit Connect.app/Contents/MacOS/Fitbit Connect Menubar Helper.app)
        Airfoil Speakers    Application Hidden (/Applications/Airfoil Speakers.app)
        Printer Pro Desktop    Application  (/Applications/Printer Pro Desktop.app)
    Internet Plug-ins: ℹ️
        FlashPlayer-10.6: Version: 17.0.0.169 - SDK 10.6 [Click for support]
        QuickTime Plugin: Version: 7.7.3
        AdobePDFViewerNPAPI: Version: 11.0.10 - SDK 10.6 [Click for support]
        AdobePDFViewer: Version: 11.0.10 - SDK 10.6 [Click for support]
        Flash Player: Version: 17.0.0.169 - SDK 10.6 [Click for support]
        Default Browser: Version: 600 - SDK 10.10
        Silverlight: Version: 5.1.30514.0 - SDK 10.6 [Click for support]
        JavaAppletPlugin: Version: Java 8 Update 31 Check version
    User internet Plug-ins: ℹ️
        Stamps.com: Version: 1.1.13 [Click for support]
    Safari Extensions: ℹ️
        1-ClickWeather
        Adblock Plus
        SafariRestore
    3rd Party Preference Panes: ℹ️
        Flash Player  [Click for support]
        GPGPreferences  [Click for support]
        Java  [Click for support]
    Time Machine: ℹ️
        Skip System Files: NO
        Mobile backups: ON
        Auto backup: YES
        Volumes being backed up:
            Macintosh HD: Disk size: 150.14 GB Disk used: 46.65 GB
        Destinations:
            Data [Network]
            Total size: 497.62 GB
            Total number of backups: 55
            Oldest backup: 2014-03-29 22:27:52 +0000
            Last backup: 2015-04-17 03:29:42 +0000
            Size of backup disk: Excellent
                Backup size 497.62 GB > (Disk size 150.14 GB X 3)
    Top Processes by CPU: ℹ️
             4%    WindowServer
             1%    fontd
             0%    Fitbit Connect Menubar Helper
             0%    Dropbox
             0%    AppleSpell
    Top Processes by Memory: ℹ️
        361 MB    Safari
        100 MB    com.apple.WebKit.WebContent
        86 MB    mds_stores
        86 MB    Mail
        86 MB    WindowServer
    Virtual Memory Information: ℹ️
        10.03 GB    Free RAM
        5.01 GB    Active RAM
        571 MB    Inactive RAM
        1.57 GB    Wired RAM
        1.63 GB    Page-ins
        0 B    Page-outs
    Diagnostics Information: ℹ️
        Apr 16, 2015, 09:53:12 PM    Self test - passed
        Apr 16, 2015, 11:11:30 AM    /Library/Logs/DiagnosticReports/CalendarAgent_2015-04-16-111130_[redacted].cras h
        Apr 15, 2015, 12:23:01 PM    /Library/Logs/DiagnosticReports/com.apple.WebKit.WebContent_2015-04-15-122301_[ redacted].cpu_resource.diag [Click for details]
        Apr 14, 2015, 06:55:26 PM    /Users/[redacted]/Library/Logs/DiagnosticReports/Mail_2015-04-14-185526_[redact ed].crash
        Apr 14, 2015, 02:47:54 AM    /Library/Logs/DiagnosticReports/CalendarAgent_2015-04-14-024754_[redacted].cras h

    Will try.  There are no cables/exterior connections involved here.
    Oddly enough, this worked.  I was unable to hear anything in Safe Mode, so just exited and rebooted (yes, I'd already tried rebooting, with no effect).  Gave iTunes a shot, and am now back to normal.
    Whatever works!
    Thank you.
    bkb

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