No shortcuts or drag&drop, even after prefs reset

I'm seeking help with the following issue.
I'm running CS5 Standard (English version) on Windows 7 (Dutch version) on an account with admin rights. A few days ago all keyboard shortcuts in Indesign suddenly stopped working.
Upon this discovery I reset my preferences by deleting them and restarting Indesign. Still no shortcuts.
Next attempt: run Indesign as administrator. Ah, my shortcuts reappeared, but now I cannot drag and drop external files into my Indesign documents anymore. I get the circle with slash symbol when I hover above my document.
One thing I noticed: in the past (and currently still in the other apps in CS5) the preferences were stored in a folder named en_GB. When I run Indesign as admin, this folder gets regenerated after deleting preferences. But when I run Indesign normally, it generates a folder named en_US. So I guess Indesign suddenly thinks it's American instead of British.
What's going on here, and what can I do about this? I'm at a loss...

Hello wdienst. It sounds like you are experiencing a problem with the motherboard. There are two pieces of information which are alarming. The first is that the serial information (service ID and UUID) is now gone from the notebook. There are not many easy ways to accomplish this and getting the information back onto the board requires specialized tools only (as far as I know) available at HP Certified Repair Centers. The other thing is that the hard drive is in a known working state (because it works in another machine). To me, the fact that it is still not recognized (or gets stuck in a boot loop) implies that there may be an issue with the motherboard itself or the controller which the hard drive connects to.
This notebook is going to have to be sent to a HP repair center to have the service ID issue resolved. US/Canadian customers can contact HP Support by calling 1-800-474-6836. Residents of other countries will need to visit HP Support Worldwide to get their country's contact information.
I hope this is helpful; have a great day!
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