None of my Apple apps will open

I think I may have screwed some things up when I tried to install Wineskins. I changed a couple of permissions, and now none of my Apple apps (Textedit, Preview, iBooks, Maps, etc...even Terminal) will launch. I've tried to go back and change things back to the way they were, with no luck. They don't launch if I sign in as a guest, or if I create a new user.
I've looked at similari
I'd appreciate any help anyone has to give!
Thanks,
Steve

My second paragraph was supposed to be: I've looked at similar issues people had when upgrading to Lion, but none of the solutions have worked.

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