Not able to open SharePoint 2010 Site in SharePoint Designer 2010

Hi all,
I have SharePoint 2010 Environment and when I try to open the site in SharePoint Designer with the regular URL (https://xyz.com)
some time i am getting error "'The server sent a response which SharePoint Designer could not parse. If you are trying to connect to a Microsoft SharePoint Foundation server, check with the server's administrator to make sure Microsoft
Foundation is installed properly" and some time its work fine and open the site without any issue... but when i try to open the site with the internal URL like (http://Servername:Port) it work perfectly.
Even i am not able to open the custom workflow in SharePoint designer whenever i am able to open the site with my regular URL (https://xyz.com) and getting error "Failed to load the configuration file for the workflow", but with
the Internal URL (http://Servername:Port) i am able to open that workflow without any issue.
Please suggest!!!

Hi NaveenKSah,
According to your description, my understanding is that you got an error when you opened AAM url of a site with SharePoint 201o Designer.
Please try to add <remove verb="*" path="*.asmx" /> after <httpHandlers> in the site web.config file, compare the result.
Note: before changing the web.config file, please make a backup for the file.
More information, please refer to the link:
http://dishasharepointworld.blogspot.com/2010/08/server-sent-response-which-sharepoint_30.html
I hope this helps.
Thanks,
Wendy
Wendy Li
TechNet Community Support

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