Office 2010 - Excel prompts "The office File Validation feature has blocked this file from opening as it may contain harmful content"

The Excel Application opens a Windows with OK button. Reading Office has detected a problem with this file. To help protect your computer this file cannot be opened.
This only happens when opeining the Excel File via a XenApp Published Application but otherwise on, Excel Installed Desktop opens the file but with a warning RED bar on top.
Opening a RED bar is good with us. but completely unable to open is the problem. See below screenshots
Any help?
Note: I have already posted this question in
Answers
Always a learner

Hi,
Try to set the following registry key:
HKCU\Software\Microsoft\Office\14.0\Excel\Security\FileValidation\EnableOnLoad
Set DWORD to 0, then office will not validate files.
For more information, please refer to the following links:
http://blogs.technet.com/b/office2010/archive/2009/12/16/office-2010-file-validation.aspx
Jaynet Zhang
TechNet Community Support

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