Old Apps appear in Open With list

After backing up my data to another hard drive, erasing the target hard drive and doing a clean install of Leopard, I see that when I option-click a file, then select Open With, the list of applications include the apps on my backup hard drive in addition to the apps I have installed on my main drive.
I told Spotlight to exclude the backup drive but alas, only after indexing of both drives have finished.
Does anyone have a suggestion as to how I can cure this?
Thanks!

There's a registry entry that has to be changed from the previous version of Photoshop you had installed, presumably CS4. Do a search ("Find" using regedit) on the registry for "Photoshop CS4" (or your previous version, if any). Once you find it, change the entry to "Photoshop CS5" -- making sure that the complete pathway to Photoshop CS5 is accurate (correct it if it is not).

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