Outlook 2010 using Citrix Presentation server does not save mail profile, O365 Mailbox

We had on-premise exchange 2003 mailboxes which have been migrated to O365. Some users access their mailboxes(O365) using Outlook 2010 which is published using Citrix Presentation server 4.5. The AD accounts TS profile is pointing to \\%computername%\Tprofiles\template.man
These users used outlook 2003 with this config with the on premise Exchange 2003 server and it saved the outlook profile. After outlook 2010 is configured to connect to the users O365 mailbox all is fine until the user logs off and logs back in, the profile
setting is lost and has to re-setup. I should mention that Outlook does not auto discover the users mailbox but is able to if the outlook wizard is run either from desktop or RDP however that is not a concern unless these two are related
issues. I am not sure if the issue is with Citrix ( I am not a Citrix admin) and some configuration fine tuning needs to happen on that front or the issue is somewhere else, setting up a roaming profile is kind of ruled out since this was not needed
with Outlook 2003 and Exchange 2003.
What would be the best way to get this working ? any help will be appreciated.

It seems that deploying a PRF file is best based on the research as well as some of the links which Amy shared. Users are using Outlook 2010 using the /importprf switch however with outlook 2010 the " Encrypt data between Microsoft Outlook and Microsoft
Exchange" is enabled by default this causes some of the users to be continuously prompted for authentication, I was able to manually fix the issue by disabling  "Encrypt data between Microsoft Outlook and Microsoft Exchange"
Sorry cannot post images or link yet as my account is not verified...
We can't do this manually but want to modify the PRF file to disable this. So far the only documentation referring to this is for Outlook 2003 to
enable this,  it was disabled by default with this version of outlook.
It is found at
support.microsoft.com/kb/2006508
Add "http://" to the link
From this document I now know the setting is labelled - RPCEncryptData
Which needs to be changed under the
[ServiceEGS]
and
 [Exchange Global Section]
But I have no clue what values will disable it, anyone knows what values will disable it ? help would be appreciated.
Thanks in advance.

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