Outlook anywhere can RPC from external but cannot authenticate with AD

HI all,
Recently, I have this weird problem surfacing and it has been bugging me ever since. Let me start of of our current setup: we have 2 CAS/HUB running on NLB and 2 MB on CCR. All 4 are installed with E2007 Sp2. We have users accessing their mailbox internally
and externally.  We used self-signed certificate for all users so that they can use Outlook when they are not in the office. All was working fine for a few years when one day, one user bought a new notebook for us to configure. Following the procedure
like we had done numerous times, then, it prompt Outlook has to be online error
while using the external network. After checking all the Outlook over RPC settings and everything, all are configured as according to the plan and nothing has been changed. Internal network (ie using the company network ) all is ok.
Firewall has not been meddled with so I am not too sure it could be the problem. ( because other external users on their existing system are ok ).  
Can anyone kindly advice?
Thanks
Eric

Does the new computer trust the self-signed certificate?
Ed Crowley MVP "There are seldom good technological solutions to behavioral problems."

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