Outlook,Word and Excel 2010 slow on first open

I have a 3x users on my Lan with these issues. Windows 7 Pro (32bit) and Office 2010 (32bit) Quadcore 2.6Ghz 2GB Memory Exchange 2003 Cached/non-Cached mode Roaming Profiles When attachments (doc,docx,rtf,pdf,xls,xlsx) are opened from Outlook,Outlook tries
to open document, and displays orange loading line in the middle of screen. After about +30sec the document opens up, if you reopen document again immediately after opening the first time, its instantly open. Excel and Word files does not always open on first
attempt from PC or LAN, but does on second attempt. When opening files from within Word/Excel directly, it seems to be instant. Excel files sometimes open with this error "There was a problem sending command to the programme " then opens blank Excel2010. Things
we have tried: - Repair Office 2010 , no change - Uninstall restart and reinstall Office 2010 , no change - Install SP1 for Office 2010, no change - Swapped Workstation on 1 user, no change - Clear Outlook Cache - Start Outlook as Safemode - Disable DDE -
Moved/Renamed Roaming Profile folder on server, then had workstation recreate Profile I have had no luck

Hi
When you open attachment in Outlook, it will leave a copy to subdirectory under the “Temporary Internet Files” directory, you can empty
the subdirectory and restart outlook.
1.      
Click Start, click All Programs, click Accessories, and then click Run.
2.      
In the Run dialog box, type the following command (including the quotation marks), and then click OK.
"C:\Users\ username \AppData\Local\Microsoft\Windows\Temporary Internet Files\Content.Outlook"
3.      
Open the subfolder under the Content.Outlook folder whose folder name is a randomly generated sequence of letters and numbers. For example, FW0B6RID.
Note There may be more than one subfolder with a randomly generated
name under the Content.Outlook folder.
You need check following registry key make sure the value exists, and if the value contains a valid path
HKEY_CURRENT_USER\Software\Microsoft\Office\14.0\Outlook\Security
or
HKEY_CURRENT_USER\Software\Policies\Microsoft\Office\14.0\Outlook\Security
Value Name: OutlookSecureTempFolder
Data Type: REG_SZ
Best regards
William Zhou CHN
TechNet Community Support

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