P45 Platinum - not booting

Hi guys,
I built my PC in 2009 and have had 2 years of trouble free running from it.  This month it has started giving me grief!
Every time I turn it on it just repeatedly reboots after around 5 seconds.  When I press the power button all the fans spin up as do the HDD's.  There are no beeps from the motherboard and no BIOS info appears on my monitor.  It just reboots, spins everything up then reboots again etc.
I have been able to start it each time by switching the PSU off, pressing the clear CMOS button then switching back on. I've been doing this every day for about 2 weeks now.
Today it got worse.  I cleared the CMOS with the button on the back and tried to boot the system.  This time everything spins up but it doesn't reboot now.  It just runs the fans and HDD's indefinitely, until I switch the system off.  No beeps from the motherboard, no BIOS info on the monitor.  I tried clearing the CMOS again but it just does the same.  This happened once last week but I left it disconnected from the power supply overnight and I was able to switch the system on again.
When the system does switch on it runs perfectly, no error message, no slowdown etc.
The motherboard has the latest BIOS version according the MSI website, v1.60.
I'm nor sure where to start looking for a fault. I think I'm just about ready to throw it out the nearest window  
Specs -
MoBo - P45 Platinum
CPU - Intel Core 2 Quad Q9550
GPU - XFX Radeon HD4890 Black Edition
PSU - Coolermaster Real Power M520
RAM - Kingston HyperX DDR2 4GB
HDD - Samsung HD103UJ 1TB
         Seagate Barracuda 7200.12 ST31000528AS
Optical Drive - LG GGL-H20L Blu Ray drive
OS - Windows 7 64bit
Hopefully someone here has some suggestions on where I should start looking for a fault.

Just got my multimeter out and tested the 24 pin plug on the power supply.
Removed power supply from the case and used some cable to connect pins 15 and 16 to make the cooling fan spin.
Test results -
Pin          Should be              Tested
1               3.3v                     3.33v
2               3.3v                     3.33v
3               Earth                    Earth
4               5v                        5.00v
5               Earth                    Earth
6               5v                        5.00v
7               Earth                    Earth
8               5v                        5.00v
9               5v                        5.07v
10             12v                      12.17v
11             12v                      12.18v
12             3.3v                      3.33v
13             3.3v                      3.33v
14            -12v                     -10.41v
15             Earth                     Earth
16             Not sure                Nothing, but the fan worked when shorted to pin 15
17             Earth                     Earth
18             Earth                     Earth
19             Earth                     Earth
20             Not present            Not present
21             5v                         5.00v
22             5v                         5.00v
23             5v                         5.00v
24             Earth                     Earth
Pin 14 looks a little low, -10.41v instead of -12v

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    500 watt Coolermaster silent pro
    Quad 9400
    MSI P45 Platinum(Gamer serie) bios 1.6
    G.SKILL 4GB (2 x 2GB) 240-Pin DDR2 SDRAM DDR2 1066 (PC2 8500) Dual Channel Kit Desktop Memory Model F2-8500CL5D-4GBPK - Retail CAS latency 5-5-5-15
    ZALMAN CNPS 9500 AT ( CNPS9500AT ) Cooler voor processor
    Nvidia Asus GTS 250 DK top videocard
    Samsung 1 tera HD
    WD 500 gig
    WD 500 Gig
    3 fans in pc more

    befor my msi i had a asus P5q turbo with the same hardware and had no any problem with it i had also windows vista 64 bit
    Productbeschrijving  CoolerMaster Silent Pro M500 - voeding - 500 Watt 
    Type apparaat  Voeding - actieve Power Factor Correction (PFC) - intern 
    Naleving van specificatie  ATX12V 2.3/ EPS12V 2.91 
    Afmetingen (BxDxH)  15 cm x 15 cm x 8.6 cm 
    Lokalisatie  Europa 
    Input Voltage  115/230 Volt wisselstroom V 
    Geleverde energie  500 Watt 
    Output Connector(s)  4-PIN interne voeding, 4-PIN mini-stroomconnector, 15-pens seriële ATA-voeding, vermogen 8-pins +12 Volt, voeding 24-pins ATX met afneembaar 4-pins deel, 8-pins PCI Express voeding met afneembaar 2-pins deel 
    Garantie van de fabrikant  5 jaar garantie 
    Model  RS-500-AMBA-D3 RS-500-AMBA-D3 
    Type Type  Intel ATX12V V2.3 ＆ SSI EPS 12V V2.91 Intel ATX12V V2.3 & SSI EPS 12V V2.91 
    Dimension (W / H / D) Dimension (W / H / D)  150(W) x 86(H) x 150(L) (mm) 150 (W) x 86 (H) x 150 (L) (mm) 
    Input Voltage Ingangsspanning  90~264V (Auto Range) 90 ~ 264V (Auto Range) 
    Input Current Ingangsspanning  8A@115Vac, 4A@230Vac 8A @ 115Vac, 4A @ 230Vac 
    Input Frequency Range Input Frequency Range  47~63Hz 47 ~ 63Hz 
    PFC PFC  Active PFC >0.9 Active PFC> 0.9 
    Power Good Signal Power Good Signal  100~500ms 100 ~ 500ms 
    Hold Up Time Hold Up Time  >17ms > 17ms 
    Efficiency Efficiency  85% Typically 85% Typisch 
    MTBF MTBF  >100,000hrs > 100.000 uren 
    Protection Bescherming  OVP/ UVP/OCP/OPP/OTP /SCP/ OLP OVP / UVP / OCP / OPP / OTP / SCP / OLP 
    Output Capacity Capaciteit  500W 500W 
    Max. Max. Output Capacity Capaciteit  620W 620W 
    Operation Temperature Operation Temperature  0~40℃ (Nominal Input Voltage) 0 ~ 40 ℃ (Nominal Input Voltage) 
    Regulatory Regulatory  NEMKO / TUV / CE / GOST / C-tick / / UL / FCC NEMKO / TUV / CE / GOST / C-tick / / UL / FCC 
    Fan Fan  135mm ultra silent fan Ultra Silent 135mm fan 
    Certification Certificering  80 Plus 80 Plus 
    Connector Connector  M/B 20+4 Pin Connector x 1 M / B 20 +4 pins connector x 1
    CPU 4+4 Pin x 1 CPU 4 +4 pin x 1
    PCI-E 6+2 Pin x2 PCI-E 6 +2 pin x2
    4 Pin Peripheral x 5 4 Pin Peripheral x 5
    SATA x 6 SATA x 6
    4 Pin Floppy x 1 4 Pin Floppy x 1 

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