Performance Setup and Setting up SSDs and HDDs. PLEASE HELP! Newbie over here!

I am new to all of this Adobe setups and learning computer hardware. So please go easy on me.
First question. What would be the best way to setup my computer for the best performance when using After Effects and Premiere at the same time? I really don't understand this. What's the best options here when I only have 16 GB of RAM?
Second Question. How should I set my drives up? This is what I think to be correct but I would love a second opinion.
And also what's the best way to set this up for Premiere?

Start with Tweakers Page and the articles there.

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