Photoshop CS 5.1 - can't open or create files

Hi,
I have Photoshop CS 5.1 32bit and 64bit (running on 64bit windows), and sometimes it happens so that I can't open files (jpg, psd, ...) in it. When I drag and drop a file to photoshop, or click on Open file dialog, or even try to make a new document, nothing happens.
I have tried tricks with deleting preferences, but it didn't help. The only thing that helps is restarting windows - but this is not a practical solution for me.
I would expect some help from Adobe on this, since we pay a lot for their products!
Thanks,
Marek

I'm not literally "looking into it" as I'm not with Adobe nor can I reproduce the problem (and I am running Windows 7 x64 on several machines).  I'm really trying to catalyze the conversation here to help lead to a discovery.
I think, since Adobe has said they've not been able to reproduce the problem, it falls on those seeing the problem to try to isolate it further.
If it were me, I'd download and run the freeware tool Autoruns, then disable the software that's starting that you don't know you need.  Perhaps you'll discover what it is that's getting in the way of normal Photoshop operation, and can share that information here for others to use.  I actually use this tool myself regularly to keep my system clean and lean.
-Noel

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