Photoshop CS Won't Open

I have Photoshop CS and have been using it for a long time on this computer - and it has always been fine. I'm now trying to open it - and it basically won't open. The initialization takes forever (it was always long - but is REALLY long) and then I get a message that the application is not responding.
There is nothing new about the computer - no new hardware or software. And everything else runs fine.
I'm currently going through a procedure to see if I have a virus or some other kind of malware - but I'm wondering if anyone has had a similar experience - and if so, what the solution was.
Thanks in advance for your consideration.

Just found the answer to my problem. Getting rid of the twain files. Here's the link to the solution we found at another forum.
http://social.answers.microsoft.com/Forums/en-US/w7programs/thread/2ed659f5-8f3f-44d8-8a9d -a78f2abb7313
Here is the answer:
So I've been looking at this for quite a few hours over the last few days and good news!  My thanks for your suggestions, but whilst trying multiple uninstalls of various software/services/drivers I noticed that when Photoshop fails to open it stopped at the same point.  Before clicking "Look for solution online" or "Close program" I noted down that it was at the TWAIN loading screen.  TWAIN is for scanners (took me a few moments before I remembered that).  A search for "CS3 TWAIN problem" gives a few results but about third on the list for me was:
http://kb2.adobe.com/cps/330/330344.html
This is a link to an Adobe tech note that explains the exact problem I was having.  Just in case the link stops working, here are the very simple steps:
On Windows:
Go to Program Files\Adobe\Adobe Photoshop CS2\Plug-Ins\Import-Export (Photoshop CS2), or Program Files\Adobe\Adobe Photoshop CS3\Plug-Ins\Import-Export (Photoshop CS3).
Right-click the Twain_32.8BA file and choose Rename.
Add a tilde (~) in front of the name and press Enter.
Note that Photoshop will no longer talk direct to scanners, but to be honest who cares.  You can scan whatever you want using your scanning software and open the resulting image files in Photoshop.
I hope this helps others.  Plus GREAT news, CS3 really IS compatible with Windows 7.
Good luck
Larry

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