Photoshop CS4 will not Start

Hi, i'm usually quite responsible when it comes to making sure my system can coap with what i am asking of it, but i've ran into a problem that my computer just can't seem to get around, and means that photoshop cs4 will not start up.
I've been making .PAT files from a few pattern sourcebooks i've recently brought. The first two went fine, but a japanese sourcebook contained 250 reasonably hi-res pattern images which i put through an automated action which set them all as patterns for me for the Pattern Overlay option in beldning options. When i did this i noticed my computer started to slow down near the end of the process, so i saved out the .PAT file from them, and quit photoshop to free up over 2.10GB worth of data. I have 4GB on a 32bit XP, but only 2 and a half-ish is seen by windows due to the hardware installed aswell. Of course i plan to chnage this to 64bit soon, but anyway, when photoshop now is told to start up, it reads everything normally, then gets to "Reading Preferences", and crashes with an error report, which watching my task manager, i belive to be linked to memory shortage from having to load the patterns up.
I reset my preferences to see if it would set them all back to default and not read the added pattern files, but that made no difference. Any ideas?
Thanks in advance!!

I'd look into doing a couple of tests:
1.) Move those PAT files elsewhere
2.) Eliminate all programs and Processes, that are unnecessary. Task Manager>Processes will give you a list of all that load, and you can probably stop half of them with no ill effects. I'd use MSCONFIG, so you can go back and easily activate them later.
3.) Reboot and see what happens.
Note: John's suggestion on the Presets folder might address #1, but I'd also physically Move them. It sounds like you're running totally out of resources to run PS, so Textures, and such, might be an issue too.
A question: how are your Scratch Disks setup and please tell us about your I/O sub-system, i.e. the internal HDD's, their size, free space, speed, controller type and how these internal HDD's are allocated. Especially tell us if you have any physical HDD's partitioned.
Good luck,
Hunt

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