Photoshop CS5.1 - Can't save or open file

This is an issue that randomly pops up and has been popping up for a while now (also in CS4 and CS5).
Basically I will be working in Photoshop and all of a sudden I cant save the file anymore. It opens up the dialog (if i do a "save as") but after a second or two it stops, leaving the file unsaved. After this point I can't even open any more files, the "file open" dialog box opens, but no documents.
If I have a document open during this time and try to edit a type layer, it will revert to the previous variant after I commit the changes.
I also can't do a drag&drop command from that point onward.
After I reboot, it starts working again ... until the next time "it" happens.
I have openGL turned off atm, same happens with it being turned on.
Running Win7 64bit, 4GB ram, wacom intuos 3, two monitors
All drivers are updated, but as I've said before, it's an
Please help!

Everything is updated. No third party plugins are installed, just the adobe fonts are on this computer (did a fresh install cause of this issue).
Its weird because, I can't even use the free transform tool (it shows the bounding box, but I cant drag anything). Same with the text layers, can't make any permanent changes.
When I click on file/save nothing happens, file/save as opens up a dialog box, but then it's the same thing.

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EmDashMan wrote:
Hi,
I've suddenly got a major problem - I can't Save or Save As any Framemaker files.
Specifically, I am using Framemaker 9 (latest patches) under Win XP/SP3, using parallels Desktop for Mac on my MacBook Pro 17" (8GB, 2.8GHz Intel Core 2 Duo, Mac OS 10.6.2).
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Martin Ley
martin at em-dash dot com
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I'm using InDesign on my MacBookPro pre-unibody under Leopard, and also under Windows 7 Vista running on VMware Fusion2.
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