Photoshop CS6 does not open or create files

I am using Adobe Cloud. And have downloaded Photoshop CS6. Using it locally.
It was working fine.  For weeks. The application still loads without error. But if I open a file nothing happens. No error message. But no file appears. And if I try to create a new file the same thing. No error message. But no new canvas to work with. In both cases nothing appears in the layers panel.
The Help menu gives me the option of deactivating. So I am assuming it is not an activation issue.
Fireworks works fine. Illustrator works fine. Only Photoshop has this problem.
I am running Windows 8. 64bit. 12gb. NVIDIA GeForce GTX 560 2gb. Adobe Photoshop Version: 13.0 (13.0 20120315.r.428 2012/03/15:21:00:00) x64. No optional 3rd party plugins.

Update 03/2/2013
I had enough I uninstalled Creative Cloud and secure wiped the Intel 520 SSD and the wiped the RevoDrive 3 X2. Installed windows 8 clean install and re-downloaded and installed all the Creative Cloud Apps.
1. After the install was completed clicking on Photoshop CS6* causes nothing to happen. No tasks open, nothing in task manager showing photoshop opening. It's like the request just goes away.
2. Figured maybe I need the updates, opened bridge clicked on help - updates.
3. All products had updates and updated them all.
4. All updates successful except for Photoshop and DynamicLinkmanager.
Photoshop Update Failed
Adobe Photoshop 13.0.1.1
Installation failed. Error Code: U44M2P7
So then I search the forums and find the option to manually download the CS6 update from Adobe.com. I did that and still nothing. 
So in Windows 7 I could open Photoshop once per reboot and work. Now in Windows 8 I can't even get it to open.
There has to be an incompatibility with either:
1. Nvidia GTX680 4GB cards
2. Nvidia WHQL Latest Drivers
I draw that conclusion because PS CS6 has worked just fine until Nvidia Updates were installed. I know in 3D Mark III the card only reports as a 2GB and they claim it's purely cosmetic reporting. It also works fine on my Quadro 5000 card in another box.
Unable to open Photoshop CS6 in Windows 8 Pro
Unable to open using program Compatibility Troubleshooter Mode: Windows 7
Unable to open images in Adobe Camera Raw or Photoshop from within Bridge. No Errors it's like the request simply disappeared.
sniffer_GPU Report:
Device: 0000000000312F28 has video RAM(MB): 1868
Device: 00000000002FBB88 has video RAM(MB): 4095
Vendor string:    NVIDIA Corporation
Renderer string:  GeForce GTX 680/PCIe/SSE2
Version string:   3.0.0
OpenGL version as determined by Extensionator...
OpenGL Version 3.0
Has NPOT support: TRUE
Has Framebuffer Object Extension support: TRUE
OpenGL ok
OpenCL ok, version=1.1 CUDA 4.2.1
Return code: 3
PS6 Executable Digital Signature:
sha1 - Monday, January 7, 2013 12:36:15 PM
System Info From Lightroom (Since PS6 doesn't open)
Operating system:  (Build 9200)
Version: 6.2 [9200]
Application architecture: x64
System architecture: x64
Logical processor count: 12
Processor speed: 3.2 GHz
Built-in memory: 65476.6 MB
Real memory available to Lightroom: 65476.6 MB
Real memory used by Lightroom: 159.9 MB (0.2%)
Virtual memory used by Lightroom: 123.0 MB
Memory cache size: 0.0 MB
Maximum thread count used by Camera Raw: 6
System DPI setting: 96 DPI
Desktop composition enabled: Yes
Displays: 1) 1920x1080, 2) 1920x1080
System Hardware Specs:
OS Drive (Intel 520 240GB SSD)
Motherboard: Asus Rampage IV Extreme x79 Chipset
CPU: Intel i7 3930K
Memory: 64GB PC-2400 G.Skill
Adobe Creative Cloud is installed on the D:\ Drive which is an OCZ Revodrive 3 X2.
Video: EVGA GTX680 Classified 4GB Edition
Video Drivers: Nvidia 314.07, DirectX 11.0, API Version 11.1, Clock 1110Mhz
*Photoshop CS6 refers to both the x64 edition and 32bit edition. I've tried both.

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