PhotoShop launching problem

I recently switched external hard drives and now when I launch PhotoShop I get a dialog box stating:  Could not open a scratch file because the disk is not available'.  Followed by another dialog box, 'Could not initialize PhotoShop because the disk is not available.'  The old hard drive is no longer available.  I've uninstalled the program, emptied the trash, and reinstalled and the same thing happens.  Any suggestions?  THANK YOU!

Reset the prefs by holding down Ctrl+Alt+Shift during program startup or manually trash the relevant psp file in your user folder.
Mylenium

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