Photoshop wont start. Scratch disc not available

Please help. I assigned a certain drive on my Mac pro to be a scratch disc for CS4 like I did when i had a PC. Now when i try and start CS4 it stops and says "could not open a scratch file because the disc is not available" I press OK and then get "Could not initialize photoshop because the disk is not available". I uninstalled PS4 and then reinstalled but it still does it. The scratch disc I assigned is a partition of the main drive. I have no idea what to do next.

Thank you for the quick and correct answer. Almost as soon as I pushed the submit button on the problem I realized what I had done was a preference setting and remembered to go delete that file, after which all was fine. Whew

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Could not initialize Photoshop because the disk is not available

I get this message when I try to startup Photoshop:
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Does anyone know another way to fix this. It seems like this must be some "login-local" preference (meaning that there must be something in the user's local preferences for setting this scratch disk parameter (the only reason I'm thinking this is that if I create another user and run Photoshop, I get no error.)
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I just got the same message, "Could not initialize Photoshop because the disk is not available". I had just assigned my primary scratch disk to an internal drive that was empty and had lots of free space. When I restarted my machine, the error message appeared when I tried to open Photoshop.
Not sure why this error occurred, but deleting the preferences did fix that problem... unfortunately, doing that will reset all your prefs = pallets, brushes, actions. I suspect you could just delete the "Adobe Photoshop CS2 Prefs.psp" file and leave the others intact to avoid that.
I would still like to know why changing the scratch disk gives us this problem? I mean, isn't that the whole point of having another internal drive?
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Photoshop wont start. Scratch disc not available

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