Physical machines VS Virtual machines for SCOM system

Hi all,
We are about to build SCOM system which will host around 80 hosts in the beginning but it may grows up to a thousand or more hosts. We are debating whether to use virtual machines or physical machines for that purpose.  So far all SCOM systems (management
servers,DB,DW) I have dealt with are hosted on physical machines.
Can anyone provide advice based on experience regarding this issue?

Microsoft supports running all System Center 2012 – Operations Manager server features in any physical or virtual environment that meets the minimum requirements that are stated in this document. However, for performance reasons, we recommend
that you store the operational database and data warehouse database on a directly attached physical hard drive, and not on a virtual disk. Specifically, virtual computers that are running any Operations Manager server feature must not use
any functionality that does not immediately commit all activity on the virtual computer to the virtual hard drive. This includes making use of point-in-time snapshots and writing changes to a temporary virtual hard drive. This is true for every virtualization
technology that is used with Operations Manager.
You can work on SCOM virtualization and it will supported your agent but
operational database and data warehouse database on a directly attached physical hard drive, and not on a virtual disk
For more details, you can refer to below
http://technet.microsoft.com/en-us/library/jj656649.aspx#BKMK_Virtualization
http://blogs.technet.com/b/momteam/archive/2012/04/02/operations-manager-2012-sizing-helper-tool.aspx
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    >
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