Possible Permissions problems with adobe

I have been dealing with a problem with Adobe Creative Suites where Photoshop and Illustrator either crash or simply refuse to open files, "Cannot open filetype" errors.
So I attempted to reinstall the programs from the original discs twice and they still would not work. For some forgotton reason I created a new User Account on the Mac and installed Photoshop in that User and it worked perfectly. I really do not want to have two Admin users on this machine so I would like to get the first user to work properly.
Anyone know what could possibly be wrong with the permissions on the first user?
Thanks

See the steps I posted for resolving conflicts/corrupt plists in:
http://discussions.apple.com/thread.jspa?messageID=4703015

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