Pre-process a page before sending

Question

Is there anyway to preprocess a before it leave the server.
The situation is that we have pages of static content with
hundreds of glossary links in. The glossary details are stored ina
a DB. title attributes are being used to display a word's meaning
and I want a quick way to scan a page before it loads, and add in
the glossary definitions - any ideas?

Answer 1

The pages are all .cfm pages with static text in. The
glossary is stored in a DB.
Definitions are added to the page via the title attribute of
a <strong> tag e.g. <strong title="aka skaskdalskd aklak
dlk asldk al dkalkdlaksdlkas dlka slkalsdalksd lakjsdlakj sdlka
ldka sldka lskd laksj dlad">Word</strong> (this is runing
on an intranet so on IE Explorer is used and they display fine) but
there are hundredsof definitions and thousands of places where the
definitions are used. And they keep adding. So is there a way to
pre-process the page, prior to it loading. Or do we need to run a
script each time the glossary DB is updated to search for terms and
add in the definition?
Cheers
R