Preferences Grayed Out

In ISync preferences, the following choices are grayed out:
Enable syncing on this computer
Show Hot Sync reminder..etc
Reset Sync History.
Also Sync Server crashes occasionally.
I have been trying to Sync Entourage with Address Book and Ical and the sync does not happen. This is a recent problem. Before this I had no problem syncing. I have sync enabled in Entourage preferences

Try resetting Sync Services by using the Terminal command in this Support document:
http://support.apple.com/kb/TS1627

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    Have you tried resetting the SMC ?     >  Resetting the System Management Controller (SMC)

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    I have the same problem. Unfortunately, the troubleshooting link you added has the first step listed as "Verify that FaceTime is enabled in FaceTime > Preferences" which we (the original poster and I) can't do as our Preferences are greyed out. We can't click on them to verify anything.
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    Your card isn't a CUDA card.
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    In system preferences bluetooth is permanently grayed out, I can't check it on.  Same with the bluetooth symbol up in the munu bar.
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    Please read this whole message before doing anything.
    This procedure is a diagnostic test. It’s unlikely to solve your problem. Don’t be disappointed when you find that nothing has changed after you complete it.
    The purpose of the test is to determine whether the problem is caused by third-party software that loads automatically at startup or login, by a peripheral device, or by corruption of certain system caches. 
    Disconnect all wired peripherals except those needed for the test, and remove all aftermarket expansion cards. Boot in safe mode and log in to the account with the problem. Note: If FileVault is enabled on some models, or if a firmware password is set, or if the boot volume is a software RAID, you can’t do this. Ask for further instructions.
    Safe mode is much slower to boot and run than normal, and some things won’t work at all, including sound output and  Wi-Fi on certain iMacs. The next normal boot may also be somewhat slow.
    The login screen appears even if you usually log in automatically. You must know your login password in order to log in. If you’ve forgotten the password, you will need to reset it before you begin. Test while in safe mode. Same problem? After testing, reboot as usual (i.e., not in safe mode) and verify that you still have the problem. Post the results of the test.

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    In my system preferences, my sharing folder will not let me access it. All my photo booth share button is grayed out. One more thing, My photoshop will not let me import any photographs.  I believe this all has to do with this.  Any way to fix this issue?

    The iTunes Store has no phone support and never has. Contacting them has always been via web form. Go here:
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