Premiere suddenly won't start

I've had a very strange thing happen, I was working on a project in PPro 5.5 when suddenly Premiere became unresponsive and eventually crashed.  Ok, that's happened with PPro since version 1 in my experience so I just restarted the program.  Well, I got the loading screen, it went through it's "loading x" as it did all the stuff it normally does then suddenly the loading screen goes away and I'm at the desktop.  I try again with the same result, this time I'm monitoring the Task Manager.  Adobe Premiere Pro.exe appears in the processes, then suddenly it vanishes as the loading screen does.
Hmm, I then tried to reboot the computer.  After the reboot I again tried to launch PPro with the exact same results.  At this point I attempted to reinstall PPro in case my install had been corrupted, this yielded no results and the same problem persisted.  I tried Encore and Media Encoder and both of them work perfectly.
I'm about to attempt an uninstall of PPro and my MXO2 and reinstall but I'm not all that hopeful.  Has anyone seen this before?  The thing that gets me is I was working on a project before this happened.  If all else fails I guess I can format and reinstall Windows but I'd really rather avoid that extreme a step.  And of course this happens when I'm on a deadline... things never go wrong when you've plenty of time to work through problems.
Oh, I've run a virus scan (Avira AV) and come up negative.
A few specs on the  machine:
Dual Xeon 3.47GHz 6 core CPU's, 12 cores total, 24 logical cores total
Supermicro X8DTL motherboard, intel 5500 chipset
24GB registered RAM in triple channel mode
Win7 Pro 64 bit with all updates
Matrox MXO2 LE capture/playback
Nvidia GTX 580 4GB video card
Intel LSI MegaRaid SATA raid controller
7TB RAID 5 array on the RAID card
Installed software consists of PPro CS 5.5 suite, Avira anti virus and Firefox web browser.  Beyond that it's a clean install

Generally Preferences are liable to currput... Caches too..
So whenever you experience problems with any app, resort to some householding and rid yourself of
preferences and caches and other files which the application is relying on...
Glad it all worked out

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    Path: /Applications/Adobe Photoshop Elements 4.0/Photoshop Elements 4.0.app/Contents/MacOS/Photoshop Elements 4.0
    Identifier: com.adobe.Photoshop.Elements
    Version: 4.0 (20060216.m.125) (4.0)
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    Interval Since Last Report: 7584 sec
    Crashes Since Last Report: 1
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    Per-App Crashes Since Last Report: 1
    Date/Time: 2009-07-23 17:51:10.468 +0100
    OS Version: Mac OS X 10.5.7 (9J61)
    Report Version: 6
    Anonymous UUID: 2EA2E06C-C896-4A79-A14E-62734BAC1D12
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    r28: 0x00000000 r29: 0x00000002 r30: 0x00000002 r31: 0x958f50f4
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    r24: 0x00000000 r25: 0x00000000 r26: 0x00000000 r27: 0x00000000
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    0x200b0034: No symbol
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    srr0: 0x00000000 srr1: 0x00000000 vrsave: 0x00000000
    cr: 0xXXXXXXXX xer: 0x20000000 lr: 0x200ba520 ctr: 0x94e86720
    r00: 0x00000004 r01: 0xbfff8900 r02: 0x2067a448 r03: 0x220dda00
    r04: 0x00000000 r05: 0x00000001 r06: 0xfefefeff r07: 0x80808080
    r08: 0x00450050 r09: 0x220dda0c r10: 0x00000000 r11: 0x80008000
    r12: 0x80808080 r13: 0x00000000 r14: 0x00000000 r15: 0x00000000
    r16: 0x1fb04d70 r17: 0x03cc4c00 r18: 0x00000000 r19: 0x203840c4
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    r12: 0x94ea0760 r13: 0x1b71b010 r14: 0x00000000 r15: 0x1b71b010
    r16: 0x1b71b008 r17: 0xf0203e18 r18: 0x1b722efc r19: 0xf0203e0c
    r20: 0xf0203dfc r21: 0xf0203e08 r22: 0xf0203e34 r23: 0x00000000
    r24: 0x1b722efc r25: 0x1b71b010 r26: 0x00000000 r27: 0xf0203e04
    r28: 0xf0203e34 r29: 0x00000000 r30: 0x1b71b010 r31: 0x1b702efc

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