Prevent pop ups from opening in safari

Question

Despite I prevented pop ups from opening in Safari in preferences; they still keep popping up. I installed two add block extensions but in-vain.

Answer 1

There is no need to download anything to solve this problem. You may have installed a variant of the "VSearch" ad-injection malware.
Triple-click the line below on this page to select it, then copy the text to the Clipboard by pressing the key combination  command-C:
/Library/LaunchDaemons
In the Finder, select
          Go ▹ Go to Folder...
from the menu bar and paste into the box that opens by pressing command-V. You won't see what you pasted because a line break is included. Press return.
A folder named "LaunchDaemons" may open. Look inside it for a file with a name of the form
          com.something.daemon.plist
Here something is a variable word, which can be different in each case. It could be "cloud," "dot," "highway," "submarine," "trusteddownloads," or pretty much anything else.
There may also be a file named
           com.something.helper.plist
in the same folder.
Leave the LaunchDaemons folder open, and open the following folder in the same way:
/Library/LaunchAgents
In this folder, there may be a file named
          com.something.agent.plist
where the word something is exactly the same as before.
If you feel confident that you've identified these three files, back up all data, then drag the three files you found to the Trash. You may be prompted for your administrator login password. Close the windows and restart the computer.
Don't delete the "LaunchAgents" or "LaunchDaemons" folder or anything else inside either one.
The malware is now permanently inactivated, as long as you never reinstall it. You can stop here if you like, or you can remove two remaining components for the sake of completeness.
Open this folder:
/Library/Application Support
If it has a subfolder named just
           something
(where something is the same word as before), drag that subfolder to the Trash and close the window.
Don't delete the "Application Support" folder or anything else inside it.
Finally, in this folder:
/System/Library/Frameworks
there may an item named exactly
            v.framework
It's actually another folder, though it has a different icon. Drag it to the Trash and close the window.
Don't delete the "Frameworks" folder or anything else inside it.
If you didn't find the files or you're not sure about the identification, post what you found.
If in doubt, or if you have no backups, change nothing at all.
The trouble may have started when you downloaded and ran an application called "MPlayerX." That's the name of a legitimate free movie player, but the name is also used fraudulently to distribute VSearch. If there is an item with that name in the Applications folder, delete it, and if you wish, replace it with the genuine article from mplayerx.org.
This trojan is often found on illegal websites that traffic in pirated content such as movies. If you, or anyone else who uses the computer, visit such sites and follow prompts to install software, you can expect more of the same, and worse, to follow. Never install any software that you downloaded from a bittorrent, or that was downloaded by someone else from an unknown source.
In the Security & Privacy pane of System Preferences, select the General tab. The radio button marked Anywhere  should not be selected. If it is, click the lock icon to unlock the settings, then select one of the other buttons. After that, don't ignore a warning that you are about to run or install an application from an unknown developer.
Then, still in System Preferences, open the App Store or Software Update pane and check the box marked
          Install system data files and security updates (OS X 10.10 or later)
or
          Download updates automatically (OS X 10.9 or earlier)
if it's not already checked.