Program will not respond

ai. will not resond when i try and open it on my (hp / windows 7) has worked before. This is a recent development.
Please help

i have CS5 all the programs work but Ai. When i try to load the program freeze and my computer sas Ai will not respond. i have unloaded and reloaded the programs and ctrl, alt, shift click on start up im lost to how i could fix it.

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