Programs not starting since updating to Mac OSX 10.6.8

Hi,
I just upgraded my work iMac to OSX 10.6.8 after of putting it off for a few weeks.
After restarting and logging into the system after the update installed, some apps are failing to start.
Either they begin to load then self quit (Software Update), start to load once, self quit then fail to begin to load altogether in subsequent attempts (all my Creative Suite apps--PS, AI, ID, AE, FL, PR, SB--Acrobat Reader, Safari, Address Book, iTunes, Skype).
Here are the system specs:
Model:           iMac
Model ID:       iMac 11,1
Proc Name:    Intel Core i5
Proc Speed    2.66 GHz
# of Procs      1
# of Cores      4 cores
L2 Cache       256KB/core
L3 Cache       8 MB
Memory         4GB RAM
Proc IntCon    4.8 GT/s
Boot ROM V. IM111.0034.B02
SMC V.         1.54f36
Are there any known issues regarding this update?
Thanks for any help.

You might want to try the so-called Combo Update for 10.6.8 which includes all updates from SL since the very first release (see here http://support.apple.com/kb/DL1399).
Applying this combo update mostly fixes any upgrade issues.
If this might not help either, restart from your SL disk and run Disk Utility to repair the hard disk and the permissions.

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