Programs will not open from Dock

I have updated my Macbook Pro with Yosemite which has led to - a lot. Programs will not open from Dock, they are just revealed in Finder. Scrolling with mousebuttons in a browser will zoom instead of scroll, the courser will not change after changing tool in Indesign. Just to mention a few problems i have discovered so far. I think I was an idiot to uppgrade to Yosemite. PLEASE HELP!

Open Disk Utility and Repair Permissions, then quit DU and Restart the MBP.  If that does not clear the issues, restart again holding the Command and R keys, and from Utilities on the menu bar select Install Mac OS X.  That will reinstall Yosemite but leave your content and settings intact.  See if that repairs whatever is broken.

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