Quicktime Can't open files after 10.4.10 update

I thought I had escaped all problems after installing the 10.4.10 combo updater, repairing permissions, etc. But today while trying to watch the iPhone Guided Tour video I discovered that Quicktime can't open it, nor anything else for that matter. Can't open audio files of any type, nor any video format. I have the current version of Quicktime, and after reinstalling it and reinstalling the combo updater, the situation remains broken. Quicktime Player will launch, but only to an error message :"Error Opening Movie. The movie could not be opened."
Curiously I can watch the iPhone movie in iTunes. And all other audio formats supported by iTunes play as usual. Any suggestions?

Hey Douglas,
Would you mind expounding on this .... there is more than one Library.
In the "main" (not the house user library) I did find a file in the Quick Time folder "Toast Video CD Support.qtx", and I removed it (that was the only file in there). Still getting the gray ? mark.
Trying everything suggested in this forum and then some ... no good.
did you try removing 3rd party codecs from the
/Library/Quicktime folder to see if one of them has a
conflict with the update?

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