Reduce File Size - File smallest with Acrobat 4.0/5.0 compatibility

This is with Acrobat 8.
Contrary to the information on the Reduce File Size dialog which says, Setting Compatibility to later versions of Acrobat will allow greater reduction in file size, I have a number of PDF files which gain the most reduction in size when set to Acrobat 4 and later.
Here is the various sizes by Acrobat revision chosen for one of the documents:
Make Compatible With
File Size
Retain Existing
79,202,311
Acrobat 4.0 and later
19,884,757
Acrobat 5.0 and later
19,884,773
Acrobat 6.0 and later
27,611,913
Acrobat 7.0 and later
27,611,909
Acrobat 8.0 and later
27,611,920
After the conversion when the file is reopened in Acrobat the file appears the same visually.
So the question is, am I losing any content by choosing the reduction to the smaller file size of Acrobat 4.0/5.0?
As I have a large number of these files the additional space saving would be good but not at the loss of significant information.
Thanks,
Jay

You will lose any information that is not compatible with AA4 or AA5. It may be that the information is not needed and so there is no visual difference.

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