Reinstalled 10.6.3 and now several days later the mail buttons 'send' 'reply' 'reply all' are frozen

reinstalled 10.6.3 and now several days later the mail buttons 'send' 'reply' 'reply all' are frozen (not greyed out, just completely unresponsive).  also every other keystroke or so in the body of the email returns an alert bleep (but the charactor seems to be entered without a problem).  i can recieve mail and all the "connection status" checks in Mail Connection Doctor return posative connections.  so far i tried removing the com.apple.mail.plist permissions from my library and then repairing permissions with disk utility, as well as running applejack.  no luck.  any suggestions?

Hmmm, interesting problem & not on 10.6 at the moment, but quit Mail & in the Finder go to...
Users/YourUserName/Library/Mail
Do a Get Info & see if it's locked or what rights are there.

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