Relaying using Load Balancer

Hi
Two node Exchnage 2010 DAG. All server roles on the same boxes.
CAS high availability using Cisco load balancer.
We have some applications they are relaying using Exchange 2010 Hub. They are configured using the vip of the load balancer.
The problem is, that they are unable to relay to external recipients, internal is no problem. Using the Hub directly works fine.
What could be the problem?
Regards
Peter

For those who still monitor this thread,
The issue here is that the HLB is not configured to Use Source IP.  In the Netscaler world, this is configured on a device or load balancer level and is referred to as USIP.  (Use Source IP)  If Source IP is not configured, the HLB will pass
the traffic to Exchange using the HLB's interface.  You can configure this IP as an allowed IP address on your relay connector, but this is a big security risk as previously stated because all traffic that is routed through the HLB has rights to relay.
Concerning the network guy in PeterN22's post, open connections can be a problem and can cause port saturation if you are using an (*) as a wildcard on your RPC load balancing service.  I have had much better luck, across all my load balanced deployments
(Citrix, Kemp, Cisco, etc.), when I use static port assignments on all load balanced services.  For example:
SMTP - 25
RPC - 59532
OAB - 59533
HTTPS - 443
POP - 110
etc.
Exchange 2013 load balancing is now stateless and doesn't rely on Source IP, but this same issue with SMTP will occur if Source IP is not used.  I know this is a recap of some of the other posts, but hopefully the additional information is helpful for
someone who may come across this post.

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