Replaced 4 GB with 8 GB and still slow with OSX 10.9.5

I have an early 2011 Mac Book Pro, with OSX 10.9.5.  Was very slow in boot up and especially with Microsoft Office applications.  I replaced the 4GB memory with 8 GB.  This does not seem to have helped.  Any suggestions?

Realized that I was not logged in when I emailed you.  Thanks for your response.
Here is the EtreCheck output:
EtreCheck version: 1.9.15 (52)
Report generated September 28, 2014 at 12:33:30 PM CDT
Hardware Information: ?
  MacBook Pro (15-inch, Early 2011) (Verified)
  MacBook Pro - model: MacBookPro8,2
  1 2.3 GHz Intel Core i7 CPU: 4 cores
  8 GB RAM
Video Information: ?
  Intel HD Graphics 3000 - VRAM: 512 MB
  AMD Radeon HD 6750M - VRAM: 1024 MB
  Color LCD 1440 x 852
System Software: ?
  OS X 10.9.5 (13F34) - Uptime: 0 days 17:23:9
Disk Information: ?
  TOSHIBA MK7559GSXF disk0 : (750.16 GB)
  S.M.A.R.T. Status: Verified
  EFI (disk0s1) <not mounted>: 209.7 MB
  Macintosh HD (disk0s2) / [Startup]: 749.3 GB (437.53 GB free)
  Recovery HD (disk0s3) <not mounted>: 650 MB
  MATSHITADVD-R   UJ-8A8 
USB Information: ?
  Apple Inc. FaceTime HD Camera (Built-in)
  Apple Inc. BRCM2070 Hub
  Apple Inc. Bluetooth USB Host Controller
  Apple Inc. Apple Internal Keyboard / Trackpad
  Apple Computer, Inc. IR Receiver
Thunderbolt Information: ?
  Apple Inc. thunderbolt_bus
Gatekeeper: ?
  Mac App Store and identified developers
Kernel Extensions: ?
  [not loaded] com.roxio.BluRaySupport (1.1.6) Support
  [not loaded] com.roxio.TDIXController (2.0) Support
Launch Daemons: ?
  [loaded] com.adobe.fpsaud.plist Support
  [loaded] com.microsoft.office.licensing.helper.plist Support
  [loaded] com.oracle.java.JavaUpdateHelper.plist Support
Launch Agents: ?
  [not loaded] com.adobe.AAM.Updater-1.0.plist Support
User Launch Agents: ?
  [loaded] com.adobe.AAM.Updater-1.0.plist Support
  [loaded] com.adobe.ARM.[...].plist Support
  [running] com.google.Chrome.framework.plist Support
  [loaded] com.google.keystone.agent.plist Support
  [failed] com.leadertech.PowerRegister.EPS2.365962302bf853a1c2af457c224132c1.plist Support
  [loaded] ltcm.plist Support
User Login Items: ?
  EEventManager
  Dropbox
  Microsoft Outlook
  Safari
  Evernote
  Microsoft Database Daemon
  Calendar
  AdobeResourceSynchronizer
  EEventManager
Internet Plug-ins: ?
  Flip4Mac WMV Plugin: Version: 3.3.1.3   - SDK 10.8 Support
  FlashPlayer-10.6: Version: 15.0.0.152 - SDK 10.6 Support
  Default Browser: Version: 537 - SDK 10.9
  AdobePDFViewerNPAPI: Version: 10.1.12 Support
  AdobePDFViewer: Version: 10.1.12 Support
  Flash Player: Version: 15.0.0.152 - SDK 10.6 Support
  QuickTime Plugin: Version: 7.7.3
  SharePointBrowserPlugin: Version: 14.4.4 - SDK 10.6 Support
  Silverlight: Version: 5.1.20913.0 - SDK 10.6 Support
  JavaAppletPlugin: Version: Java 7 Update 55 Check version
Safari Extensions: ?
  1Password-2
Audio Plug-ins: ?
  BluetoothAudioPlugIn: Version: 1.0 - SDK 10.9
  AirPlay: Version: 2.0 - SDK 10.9
  AppleAVBAudio: Version: 203.2 - SDK 10.9
  iSightAudio: Version: 7.7.3 - SDK 10.9
iTunes Plug-ins: ?
  Quartz Composer Visualizer: Version: 1.4 - SDK 10.9
User Internet Plug-ins ?
  Google Earth Web Plug-in: Version: 7.1 Support
3rd Party Preference Panes: ?
  Flash Player  Support
  Flip4Mac WMV  Support
  Perian  Support
Time Machine: ?
  Skip System Files: NO
  Mobile backups: ON
  Auto backup: YES
  Volumes being backed up:
  Macintosh HD: Disk size: 697.84 GB Disk used: 290.36 GB
  Destinations:
  Peter Scanlan's Time Capsul [Network] (Last used)
  Total size: 2 TB
  Total number of backups: 60
  Oldest backup: 2013-10-13 21:47:45 +0000
  Last backup: 2014-09-28 17:10:03 +0000
  Size of backup disk: Adequate
  Backup size 2 TB > (Disk used 290.36 GB X 3)
  Time Machine details may not be accurate.
  All volumes being backed up may not be listed.
Top Processes by CPU: ?
      3% WindowServer
      3% Microsoft Outlook
      1% com.apple.WebKit.Plugin.64
      0% launchservicesd
      0% fontd
Top Processes by Memory: ?
  279 MB mds_stores
  213 MB com.apple.WebKit.WebContent
  180 MB Safari
  172 MB softwareupdated
  139 MB Evernote
Virtual Memory Information: ?
  3.13 GB Free RAM
  3.13 GB Active RAM
  417 MB Inactive RAM
  1.33 GB Wired RAM
  885 MB Page-ins
  0 B Page-outs

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