Reply and send button look active, but do nothing, Safari also troubled

I do not get any errors that I can't send, Connection doc. indicates all connections are good. Emails just sit in the draft box. Also, when typing, my space bar forwards me to the bottom of the email field in Mac Mail, or the bottom of the web page in Safari. Additonally, the cursor doesn't move when using the space bar, but the space is there. When I start typing after this, sometimes my typing is backwards, it actually starts typing right to left, this also happens in Safari, but not always. The delete key sometimes highlights the text, and then, in Safari only, the program quits.
I had issues long ago with the version of MS office (2003) and OSX 10.3, but I don't remember what resolved this, I think it had somethng to do with a plist. This only happens to my main log in. Other log ins seem to be fine.

Hi labw, and a warm welcome to the forums!
At this point I think you should get Applejack...
http://www.versiontracker.com/dyn/moreinfo/macosx/19596
After installing, reboot holding down CMD+s, (+s), then when the DOS like prompt shows, type in...
applejack AUTO
Then let it do all 5 of it's things.
At least it'll eliminate some questions if it doesn't fix it.
The 5 things it does are...
Correct any Disk problems.
Repair Permissions.
Clear out Cache Files.
Repair/check several plist files.
Dump the VM files for a fresh start.
First reboot will be slower, sometimes 2 or 3 restarts will be required for full benefit... my guess is files relying upon other files relying upon other files!
Disconnect the USB cable from any UPS so the system doesn't shut down in the middle of the process.

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