RFx change options in RFx document

Hi Gurus,
What's the difference between the following two options in RFx document?
- "Bidder Can Change RFx Responses" at RFx header level
- "Allow RFx Response Modification" at RFx item level
Best regards,
Jack

- "Bidder Can Change RFx Responses" at RFx header level
This option allows the bidder to change a submitted RFx response (without buyer's initiative, such as returning the RFx response).
- "Allow RFx Response Modification" at RFx item level
This option allows the bidders to provide suppliment, substitute or alternative items to line items in an RFx.

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