Saffire 6 USB "conflict" with Garageband?

My Saffire 6 USB interface worked beautifully yesterday, but not today.  I have installed no new updates between then and now.
I'm on a MBP, running 10.9 w/ 6.0.6 (428.5).
I've got my Saffire 6 plugged into the first USB port (closest to the headphone jack).
As soon as I plug it in, I receive prompts ("New Device" and then "Number of Midi Inputs has Changed").
Yesterday, I clicked through these prompts and was able to use the Saffire effortlessly.  I monitored through the interface rather than the computer.  It sounded great.
Today, I received the same prompts but receive an "Error While Trying to Synchronize Audio and Midi" prompt.  The rest of the prompt says (verbatim): "Sample Rate 9896 Recognized. Check Conflict Between GarageBand and External Device."
i should add that the sample rate number is different every time.
I have my audio resolution set to "better," just as I did yesterday, when this thing worked with no effort whatsoever.
Little help?

HangTime wrote: "open the Audio MIDI Setup utiity and make sure your interface is set to a 44100 sample rate"
I write:  yes, that is how it was set yesterday, and that's how it's set today.  Still not working.
The thing that really gets me is that I'm doing exactly what I did yesterday, it worked beautifully, and I'm getting nowhere today.
I should also add that I have the latest drivers for the Saffire 6, before someone posts to tell me to get the latest drivers.
Thanks for your reply, HangTime.  What now?

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