Satellite C650D-12C No bootable device - Insert boot disk & press any key

Hi,
I have a C650D that was working fine up to a week ago.
It shut down ok, but refused to start up on the next boot.
It comes up saying 'No bootable device -- Insert boot disk & press any key'.
So I stuck in a bootable recovery dvd and the same thing came up, but although the dvd drive 'twitched' when I inserted the disk, it didn't seem to look at it at all when I rebooted.
I rebooted again & pressed F12 to check the boot order. 1st is usb, then cd/dvd, lan, fdd, then hdd/ssd.
I selected cd/dvd and after a few seconds' wait it said 'A disk read error occurred. Press ctrl+alt+del to restart.
Both the harddrive & the dvd drive show up correctly in the bios.
I plugged in a usb dvd drive, put in a recovery cd, rebooted & it started to boot from the usb drive, but then stopped doing anything after the first bit of info came up on the screen.
I tried several bootable cds and they all do the same. They start booting, then freeze. For example, if I put in an XP install disk I get - 'Press any key to boot from cd drive' (the usb one), then 'Setup is inspecting your hardware', then a black screen.
I've tried changing anything that might help in the bios, SATA controller mode, for example, but nothing has any effect on the situation.
Any ideas anyone please?
Many thanks.
EDIT:
I just tried booting from the usb drive with the harddrive removed from the system and the boot process continues normally. If I try & boot from the internal dvd drive though it still fails to see any disk.........

> I just tried booting from the usb drive with the harddrive removed from the system and the boot process continues normally. If I try & boot from the internal dvd drive though it still fails to see any disk.........
Does this mean that if you remove the HDD you can boot from the USB flash drive, but you cannot boot from CD/DVD drive even if the HDD is removed?
It sounds really strange but I think this would mean that either the SATA controller on the motherboard is faulty and therefore its not possible to boot from HDD or CD/DVD drive. Or it could be also possible that HDD and ODD malfunctions. But it would be really strange that both devices would start to malfunction at the same time
So possibly the second idea is not true however, this would mean that something happened to the motherboard.
But try this: access the BIOS pressing F2 at the beginning. Now set it to default settings pressing F9 and then save the changes pressing F10.
Now try to boot again using an Recovery disk

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Satellite C650D-12C No bootable device - Insert boot disk & press any key

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